UC-II® is a biologically active and immunomodulatory nutrient. The main mechanism of UC-II® is that it works with the immune system and reduces cytokine levels. MSM is a sulfur compound, a nutrient, with anti-inflammatory and antioxidant properties while participating in the creation of connective tissue, such as in joint cartilage. Glucosamine is a component found in the shell of shellfish. It has anti-inflammatory properties and contributes to the lubrication of the cartilages, inhibiting their deterioration. It also contains nicotinamide which contributes to the normal functioning of metabolic processes aimed at energy production, such as the production and secretion of intercellular substances (glycosaminoglycans, collagen, non-collagenous proteins) by chondrocytes, thus supporting bone and joint health. Ingredients Supplement Facts - Amount Per 2 capsules Nicotinamide (vitamin B3) 200 mg Glucosamine sulfate (2KCL) 420 mg  of which Glucosamine sulfate 300 mg  MSM 500 mg UC- II® 40 mg  Contains glucosamine from crustaceans, not to be consumed by people allergic to crustaceans. Free from chemical excipients, artificial colourings, artificial flavors, artificial sweeteners, gluten, gmo's. How to use Take two capsules daily during the evening or according to the directions of your doctor. Do not exceed the stated recommended daily dose. Contains glucosamine from crustaceans, not to be consumed by people allergic to crustaceans. Food supplements should not be used as a substitute for a varied diet. The product is not intended to prevent, cure or treat a human disease. Consult your doctor before consuming the product if you are pregnant, breast feeding or under medication. Keep out of reach of young children.